P-Shot: A Promising Novel Treatment for ED, Peyronie’s and More
‘P-Shot’ or ‘Priapus shot’ is a new way of treating erectile dysfunction currently offered by over 1,000 doctors in the US alone. The protocol for this therapy has been invented by Dr. Charles Runels of Alabama and is protected by the US Patent & Trademark office. It involves injecting the patient’s own platelet-rich plasma, or PRP into the penis. PRP is obtained by centrifuging blood to remove red blood cells and to increase the concentration of growth factors. The advocates of PRP therapy for erectile dysfunction like Dr. David Hozland, for example, claim that it promotes revascularization of the penis, increases its length and girth and helps correct nerve damage if there is any.
The technology behind P-shot has been used since 1980s – first in maxillofacial surgery where PRP also played the role of a regenerative agent and then in other spheres of medicine including cardiac, pediatric and plastic surgery, dermatology, gynecology, urology and ophthalmology. Although there are multiple researches both purporting and refuting the effectiveness of PRP treatment, as this article by Wang and Avila shows, its safety is out of question.
Since the concept of using growth factors for treatment of erectile dysfunction was first introduced in 2003, there isn’t much registered evidence of its effect in humans yet. The largest study carried out so far took place in 2015 in India and involved 1,220 patients who received combined treatment for penis enlargement. The author of the study, Dr. C.S. Kumar, used PRP injections and vacuum pump therapy in his patients. He reported average penis size increase of 7mm in length and 5mm in girth per injection at a follow-up 6 months after the treatment course. 70% of the patients were satisfied with their erection quality. Smaller studies showing positive outcomes of PRP treatment for erectile dysfunction were also published by Matz et al in 2017 and Chalyj et al in 2015. Additionally, the former of these two studies mentions that PRP can be used to treat Peyronie’s disease.
There are also multiple animal studies focusing on the effect PRP has on male sexual function. For example, two articles by Wu et al dating back to 2012 and 2013 show that PRP helped lab rats with cavernous nerve injury restore the ability to get erections. Cavernous nerve (CN) injury is a common complication of radical prostatectomy. It also affects the way people respond to treatment with PDE-5 inhibitors like Viagra. Up to 50% of men with CN injury can’t get an erection even with ED pills, so an alternative treatment is highly sought after.
According to the information stated in the directory of P-shot providers, this therapy can be combined with low-intensity extracorporeal shockwave therapy, aka GAINSWave, for added effect. GAINSWave includes using sound waves to create a minor inflammation inside the patient’s penile body thus promoting its revascularization, better blood flow and, consequently, higher erection quality. The positive outcome of the combined therapy has been described by Ben Greenfield of Men’s Health, among other patients.
A typical P-shot procedure comprises up to 5 injections given one after another on the same day and costs around $2,200 in the United States. Patients looking for a chance to get it at a lower cost may consider treatment abroad – for example, in Canada where it costs $1,500. Moreover, there’s history of discount P-shot offers on Groupon, for example, so monitoring similar resources is an option too.
A procedure similar to P-shot called the ‘O-shot’ or ‘Orgasm shot’ is performed in women suffering from low sex drive, weak orgasms or dyspareunia – a condition characterized by pain during intercourse common in post-menopausal patients.
Just like any other novel therapy, P-shot is not universally accepted by the medical community. Dr. Sheldon Marks, for example, doubts that it can lead to a permanent increase in penis size. Dr. Marks supposes that the reported length and girth gains are due to the temporary effect of the injection comparable with that of fillers used for lip augmentation.
While more experimental and clinical evidence is required to prove the effectiveness of platelet-rich plasma injections for erectile dysfunction for certain, it certainly is one of the promising new treatments to keep an eye on.
- Directory of healthcare providers offering P-shot therapy in the United States - http://www.priapusshot.com/members/directory/
- Dr. David Hozland on PRP for erectile dysfunction - https://www.davidghozland.com/p-shot-penile-rejuvenation/
- HL Wang, G Avila, PRP: Myth or Reality? - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2609914/
- A Martinez-Martinez et al, PRP: Myth or Reality? - https://www.ncbi.nlm.nih.gov/pubmed/30274850
- MB Siroky, KM Azadzoi, Using vascular growth factors to treat ED - https://www.auajournals.org/article/S0022-5347(05)63316-2/abstract
- CS Kumar, Combined PRP and vacuum pump treatment for penis enlargement - https://www.jsm.jsexmed.org/article/S1743-6095(16)30656-7/fulltext
- EL Matz et al, Safety and feasibility of PRFM injections for common urologic conditions - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5754585/
- ME Chalyj et al, Intracavernous autologous PRP injections for treatment of erectile dysfunction - https://www.ncbi.nlm.nih.gov/pubmed/26665770
- YN Wu et al, The neuroprotective effects of PRP injections on erectile function - https://www.ncbi.nlm.nih.gov/pubmed/22906160
- YN Wu et al, The effect of PRP on the recovery of sexual function after cavernous nerve injury - https://www.ncbi.nlm.nih.gov/pubmed/23950105
- AR McCullough, Sexual dysfunction after radical prostatectomy - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1477599/
- Taking P-shot after GAINSWave - https://www.menshealth.com/sex-women/a19540927/stronger-erection-shot/
- Price of P-shot treatment in the US - https://www.antiagecr.com/p-shot-price-frequently-asked-questions-costs-less
- Price of P-shot treatment in Canada - https://www.thegenomicclinic.com/priapus-shot-edmonton-p-shot
- Archived P-shot and O-shot discount offers on Groupon - https://www.groupon.com/deals/the-prp-institute
- Criticism of PRP injections for penis enlargement - https://blogs.webmd.com/mens-health/20160627/can-prp-injections-really-give-you-a-bigger-penis